Genetic Mutations, Cancer and Population Genetics

Objectives for the chapter and helpful videos/songs/charts are listed below. This is not an all inclusive list of the content, but it is an excellent place to start or review! The videos are used as a study tool and may cover more or less than what we will cover in class. I will not test you on anything we did not cover in class, unless stated otherwise.


Chromosomal and Genetic Changes

Changes Affecting the Number of Chromosomes 6.1 (Pg. 129-133)

  1. Explain the difference between euploidy and aneuploidy
    1. Aneuploidy- Wikipedia
    2. Definition of Euploidy
  2. Discuss the advantage of polyploid organisms
    1. Advantages of Polyploidy in Plants- Webpage
  3. Describe how nondisjunction affects the chromosome number
    1. Nondisjunction (Trisomy 21) – An Animated Tutorial

Mutations 6.2 (Pg. 133-137)

  1. Define mutation
    1. Mutations: The Potential Power of a Small Change
      1. Note: This video covers both objectives 1 and 2 for this section.
  2. Compare and contrast the changes within a chromosome and changes within a gene
    1. Types of Chromosomal Mutations- Table
    2. Point Mutations- Gene mutations
      1. Note: For the Missense mutation, conservative means that the mutation has a neutral effect on the gene, whereas nonconservative means there is a negative effect on the gene
  3. Discuss the differences between somatic and germ cell mutations
    1. Definition of ‘Somatic’ Cell
    2. Definition of ‘germ-line’ cell
    3. Somatic vs. Germ-line mutations- Picture

Gene Expression 6.3 (Pg. 137-142)

  1. Define gene expression and cellular differentiation
    1. Gene Expression- Webpage
    2. Cellular Differentiation- Webpage
    3. Cellular Differentiation-Image
  2. Compare and contrast molecular and environmental controls on gene expression
    1. Molecular Gene Expression
    2. Environmental Effects of Gene Expression- Epigenetics
      1. Note: Epigenetics is not mentioned in your text book, but I think it is beyond fascinating! You should look it up!
  3. Explain the relationship between cancer and the functions of proto-oncogenes and tumor suppressor genes
    1. Tumor Suppressor Genes
    2. Tumor suppressor and oncogenes

Population Genetics

The Gene Pool 6.4 (Pg. 142-146)

  1. Explain the difference between population and gene pool
    1. Definition of a Population (In first paragraph)- Wikipedia
    2. Gene Pool Definition
  2. Discuss how mass selection, hybridization, and inbreeding affect the gene pool
    1. Pg. 143-145
  3. Describe desirable as well as undesirable effects of hybridization
    1. Pg.146
      1. Note: I could not find very good links for these two objectives, so if you find anything, please let me know!

Eugenics 6.5 (Pg. 146-151)

  1. Define eugenics
    1. Definition of Eugenics
    2. Controversy of Intelligence: Crash Course Psychology #23
      1. Note: This is a fascinating video on challenging our view of “what” intelligence is and the ethical dilemmas that come with intelligence “testing” and eugenics.
  2. Describe the current methods of genetic screening
    1. Pedigree Analysis
    2. Analysis of the Unborn (Pg. 148-149)
    3. Newborn Screening
    4. Newborn Screening for PKU- Real Footage
    5. More Genetic Test-Webpage
      1. Note: You only need to be able to describe the three genetic screening methods listed in the text
  3. Describe the two methods of artificial reproduction
    1. In Vitro Fertilization- 3D animation
    2. Intra-Uterine Insemination
'Yes, I'm the original spiderman. Of course, they changed a lot of stuff for the comic books...'
‘Yes, I’m the original spiderman. Of course, they changed a lot of stuff for the comic books…’

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